探索促炎饮食和慢性肝病之间的关联:来自英国生物银行的证据
Lili Pan1,2, Zhengrong Xu1, Yining Li1
1Fujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China.
Frontiers in nutrition
|February 11, 2025
概括
通过饮食炎症指数 (DII) 测量的促炎症饮食显著增加慢性肝病 (CLD) 风险. 采用抗炎饮食可能有助于预防和管理CLD.
科学领域:
- 营养科学 营养科学
- 肝病学 肝病学是一种肝病学.
- 流行病学 流行病学
背景情况:
- 慢性肝病 (CLD) 是一个重大的全球健康挑战.
- 预炎性饮食被怀疑会加剧CLD风险.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 调查DII与患有CLD的风险之间的关联.
- 探索饮食炎症潜力和CLD发病率之间的关系.
- 评估饮食对慢性肝病风险的影响.
主要方法:
- 利用了来自121,329名参与者的英国生物库数据.
- 根据饮食信息计算每个参与者的DII.
- 采用了Cox比例危险和Fine-Gray竞争风险模型来分析DII和CLD关联.
主要成果:
- 较高的DII (更多的炎症饮食) 与16%的CLD风险增加有关.
- 每个单位增加的DII与3.3%的CLD风险上升相关.
- 抗炎饮食显示与CLD风险的反向关联,支持研究结果.
结论:
- 采用抗炎饮食可能有利于CLD的预防和管理.
- 饮食干预对于减轻CLD的全球负担至关重要.
- 减少饮食中的炎症潜力是肝脏健康的潜在策略.
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