在一个具有免疫能力的成年人中发生的简单疹食道炎
Richard M Bresler1, Zachary Ellis1, Foster West1
1Internal Medicine, Baptist Memorial Hospital-North Mississippi, Oxford, USA.
Cureus
|February 11, 2025
概括
简单疹食道炎 (HSE) 在免疫能力良好的人群中很少见. 这一案例突显了阿西克洛维尔的诊断和成功治疗,强调了它在非免疫受损患者中的潜力.
科学领域:
- 胃肠病学 胃肠病学
- 病毒学 病毒学
- 传染性疾病 传染性疾病
背景情况:
- 由简单疹病毒 (HSV) 引起的简单疹食道炎 (HSE) 通常是免疫受损个体的机会性感染.
- 免疫能力强的患者的HSE不常见,但通常是自我限制的.
研究的目的:
- 在免疫能力强的年轻成年人中报告一种罕见的HSE病例.
- 讨论在这一群体中HSE的诊断方法和管理.
主要方法:
- 诊断涉及临床表现,上部内镜,食道活检与组织病理学,和HSV-1聚合酶链反应 (PCR).
- 治疗是用抗病毒药物阿西克洛维尔开始的.
主要成果:
- 一个免疫能力强的19岁女性出现了恶心,吐和消化不良.
- 组织病理学和HSV-1 PCR证实了HSE的诊断.
- 患者在接受了阿西克洛维尔治疗后出现了临床改善.
结论:
- 在免疫能力较强的个体中,HSE是一种罕见但可能的诊断,呈现出食道症状.
- 临床病史,内镜,组织病理学和PCR的结合对于准确的诊断至关重要.
- 阿西克洛维尔可以有效地管理HSE,减少严重程度和持续时间,即使在免疫能力强的宿主中.
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