多抗药性Burkholderia pseudomallei肺炎被误诊为结核病:一个病例报告
Qianhui Zhou1, Yan Gao2, Yanchao Liang3
1Department of Respiratory and Critical Care Medicine, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou Hunan 412007, China. 648934631@qq.com.
概括
一个慢性Burkholderia pseudomallei肺炎病例突出了诊断方面的挑战. 在初始治疗失败后,获得了用三甲-硫甲醇的有效治疗.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 肺部病理学 肺部病理学
背景情况:
- Burkholderia pseudomallei是一种在土壤和水中普遍存在的グラム阴性细菌.
- 感染可以呈现出多样化和严重的临床表现,经常模仿其他疾病.
- 由于B. pseudomallei引起的慢性肺病并不常见,但管理起来具有挑战性.
研究的目的:
- 报告一个慢性Burkholderia pseudomallei肺炎病例.
- 为了突出诊断困难和治疗策略这种罕见的条件.
- 强调在特有病区考虑有机症的重要性,特别是在有耐治疗性肺部症状的情况下.
主要方法:
- 一个54岁的男性患有慢性呼吸道症状的病例报告.
- 诊断工作包括胸部CT,支气管支气管支气管洗液培养和活检.
- 在体外药物敏感性测试指导了抗微生物治疗选择.
主要成果:
- 这位患者最初被误诊为肺结核.
- 证实了B. pseudomallei是病原体.
- 最初用多西环素和阿莫西林-克拉夫兰酸盐治疗无效;三甲胺-硫甲醇导致完全康复.
- 该患者有过硫药物过敏史,使治疗选择复杂化.
结论:
- 慢性B. pseudomallei肺炎需要高度的临床怀疑.
- 准确及时的诊断对于有效的管理至关重要.
- 根据敏感性测试进行量身定制的抗菌药物治疗是必不可少的,即使患者病史具有挑战性.
相关概念视频
01:28Pulmonary Tuberculosis V
170
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
170
01:26Pulmonary Tuberculosis IV
132
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
132
01:31Pulmonary Tuberculosis III
296
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
296
01:28Pulmonary Tuberculosis II
211
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
211
01:29Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220