结核病并发症的时间:纵向分析
Vincenzo Calabrese1, Guido Gembillo2, Elisa Longhitano2
1Departmet of Medicine and Surgery, University of Enna "Kore", 94100, Italy.
概括
查慢性病 (CKD) 的并发症,如贫血和高胆血症,应从CKD第三阶段开始. 建议在CKD第四阶段进行高酸性查,基于估计的淋巴细胞过率 (eGFR) 值.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 慢性病 (CKD) 与许多内分泌和代谢并发症有关.
- 这些并发症显著影响患者的平衡和生活质量.
- 了解CKD阶段与并发症发病之间的关系对于及时干预至关重要.
研究的目的:
- 确定CKD阶段对特定并发症出现的影响.
- 为了确定估计的膜过率 (eGFR) 值来预测并发症的发生.
- 建立基于证据的建议,用于慢性病患者的并发症查.
主要方法:
- 一项观察性研究涉及71名患者,进行了486次测量.
- 收集的数据包括贫血,BUN,甲状腺功能障碍症,高酸血症,高血症和代谢性酸性疾病.
- 统计分析包括曼-惠特尼,皮尔森的奇方位,斯皮尔曼的相关性,GEE,线性混合模型和ROC曲线分析与Youden J指数.
主要成果:
- 慢性病阶段与所有研究结果有显著的关联.
- 确定了用于预测并发症的eGFR值:贫血 (37毫升/分钟/米2),高血 (34毫升/分钟/米2),高酸血 (26毫升/分钟/米2) 和过多甲状腺功能 (46毫升/分钟/米2).
- 基线患病率:偏甲状腺功能增强症 (69.1%),高血症 (28.6%),高酸血症 (15.5%).
结论:
- 在CKD中进行内分泌和代谢并发症查应在CKDIII期开始时开始.
- 具体的查建议包括从CKD第四阶段开始对高酸血症进行查.
- 这些发现支持主动管理策略,以减轻CKD相关的并发症.
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