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Updated: May 28, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

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自性激活纳米自体结合化合物用于针对性蛋白质降解,特别是在瘤细胞中

Mengchen Xu1, Jiajing Chen1,2, Shuyu Wang3

  • 1Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry and College of Chemistry, Nankai University, Tianjin 300071, P.R. China.

ACS macro letters
|February 11, 2025
PubMed
概括

研究人员开发了一种新的纳米-ATTEC系统,使用混合聚合物微粒 (MSPMs) 进行向蛋白质降解. 该系统增强了自性,以有效降解瘤细胞,为癌症治疗提供了一种有前途的方法.

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