与癌症和韩国普通人口相比,1型糖尿病患者的自杀风险更高
Seohyun Kim1,2, So Hyun Cho1, Rosa Oh1
1Department of Medicine, Division of Endocrinology and Metabolism, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Journal of internal medicine
|February 11, 2025
概括
与一般人口和癌症患者相比,患有1型糖尿病 (T1D) 的成年人面临的自杀风险明显更高. 这凸显了对T1D患者的心理健康支持的迫切需要.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病与增加自杀风险有关.
- 1型糖尿病 (T1D) 和癌症之间的比较自杀风险,这种疾病具有已知的心理痛苦和自杀风险,仍然不清楚.
研究的目的:
- 评估和比较T1D成年人的自杀风险与癌症患者和普通人群的匹配队列.
主要方法:
- 一项基于人口的匹配队列研究利用了韩国国家医疗保险数据库数据 (2009-2015年).
- 包括45,944名患有T1D的成年人,45,944名癌症患者和229,720名对照人群,年龄,性别和索引年份相匹配.
- 复合自杀结果包括自杀死亡或因自杀未遂住院治疗.
主要成果:
- 与对照组相比,T1D患者的复合自杀结果风险显著增加 (aHR=2.02).
- 一型糖尿病患者的自杀风险高于癌症患者 (aHR=1.75).
- 年轻 (<50岁) 和收入较低的T1D患者的自杀风险不成比例地高.
结论:
- 1型糖尿病与一般人群和癌症患者相对增加的自杀风险显著相关.
- 这些发现强调了积极的心理健康查和针对T1D患者的量身定制干预措施的急需.
相关概念视频
Psychoneuroimmunology: Diabetes and Cancer
22
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
22
Diabetes Mellitus: Overview and Type I Subtype
2.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.4K
Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
Carbohydrate Metabolism
10.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.7K
Diabetes: Symptoms, Diagnosis, and Complications
499
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
499
Insulin: Dosing Regimen and Adverse Effects
140
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
140


