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Updated: May 28, 2025

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
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Published on: August 21, 2017

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一个胆囊特异的疏水胆汁酸-FXR-MUC1信号轴介导胆固醇胆结石的形成

Hongtan Chen1, Xin Jiang1, Yiqiao Li2

  • 1Division of Gastroenterology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310002, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 11, 2025
PubMed
概括

厌水胆酸通过改变胆囊功能来促进胆固醇胆结石疾病 (CGD). 这项研究表明,缺乏CYP2C70的小鼠中改变的胆酸概况加速了CGD的形成,模仿了人类疾病.

关键词:
洞穴 (caveolae) 是一个洞穴.胆固醇胆固醇胆结石 胆结石是一种法恩索伊德的X受体是什么疏水性胆酸池的水害性 胆酸池蛋白质激酶 Cζζ 蛋白质激酶

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