住院时的形态测量脊椎骨折与长期COVID发生有关
Luigi di Filippo1, Mauro Doga1, Francesca Mangini1
1Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, via Olgettina 60, Milan, 20132, Italy.
Journal of endocrinological investigation
|February 11, 2025
概括
住院时的脊椎骨折 (VF) 与长期COVID的发展有关. 患有VF的患者在出院六个月后,无论疾病的严重程度如何,长期COVID症状的患病率更高.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 长期COVID是一种复杂的综合征,对其风险因素的研究正在进行中.
- 以前的研究表明,骨质疏松症和脊椎骨折 (VFs) 与严重的急性COVID-19和较差的呼吸系统结果相关.
研究的目的:
- 调查脊椎骨折 (VFs) 与长期COVID综合征发展之间的关联.
- 为了确定VF是否是长期COVID的独立风险因素.
主要方法:
- 对162名因急性COVID-19住院患者的回顾性分析.
- 在入院时对VF进行侧侧胸部X射线的评估.
- 排除患有活跃瘤的患者,家庭治疗或ICU入院.
- 在6个月的随访期对长期COVID诊断进行多学科评估.
主要成果:
- 42名患者 (25.9%) 在入院时至少有一次VF;他们是年长的,主要是男性.
- 在15.4%的患者中诊断出长期COVID.
- 长期COVID患者在入院时有显著更高的VF患病率 (48%对22%).
- 在匹配后,VF是长期COVID的唯一独立预测因素 (28.6%与9.5%对比).
结论:
- 在住院时常见的脊椎骨折是患有长期COVID的患者的显著临床特征.
- 由VFs表示的骨脆弱性可能与长期COVID的发展有不利关联.
- 病毒是长期COVID的独立风险因素,无论急性COVID-19的严重程度如何.
更多相关视频
07:12Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
Published on: September 28, 2017
8.1K
06:45Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
Published on: September 16, 2022
2.1K
相关概念视频
01:27Fractures: Bone Repair
2.9K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
2.9K
01:16Vertebral Column: Regions and Curvature
3.4K
The vertebral column or spine is a flexible column that supports the head, neck, and body and allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
3.4K
01:30General Structure of a Vertebra
2.5K
A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous...
2.5K