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Updated: May 28, 2025

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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Published on: June 7, 2018

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通过模仿瘤微环境来识别自然杀手细胞增强剂

Aylin Binici1,2, Elisabeth Hennes1, Sandra Koska1

  • 1Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Str. 11, 44227, Dortmund, Germany.

Chemistry (Weinheim an der Bergstrasse, Germany)
|February 11, 2025
PubMed
概括

研究人员选了小分子来克服瘤微环境 (TME) 免疫抑制并增强自然杀手 (NK) 细胞活性. 作为TGFβR-1抑制剂的RepSox通过抑制TGFβR-1和循环氧化酶1 (COX1) 两者,有效地恢复了NK细胞的细胞毒性.

关键词:
生物活动是生物活动.免疫学 免疫学 免疫学自然杀手细胞是自然杀手细胞.查检查 查检查 查检查小分子是小分子.

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