在心力衰竭中皮肤穿透的左心房尾闭塞:全国性的再接收数据库分析
Rafey Feroze1, Alexander Cove2, Yusef Saeed2
1Harrington Heart and Vascular Institute, University Hospitals, Cleveland, Ohio.
The Journal of invasive cardiology
|February 11, 2025
概括
在心力衰竭 (HF) 患者中,左心房尾闭塞 (LAAO) 没有增加中风或流血的风险. 然而,HF患者的死亡率,出血和急性损伤 (AKI) 风险较高.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏衰竭管理的管理
背景情况:
- 左心房尾阻塞 (LAAO) 是抗凝药的替代方案,用于降低心房动中风风险.
- 患有心力衰竭 (HF) 的患者可能面临增加的中风风险和手术并发症.
- 这项研究调查了LAAO结果,特别是在患有HF的患者中.
研究的目的:
- 评估LAAO在心力衰竭 (HF) 患者的安全性和有效性.
- 为了比较LAAO在患有和没有HF的患者的结果.
- 评估死亡,中风,出血和手术并发症的风险.
主要方法:
- 从2015年9月到2019年11月使用国家再接收数据库对LAAO住院病人的回顾性分析.
- 使用ICD-10代码识别患有HF的患者.
- 倾向性得分匹配 (PSM) 用于比较患有和没有HF的患者之间的结果.
主要成果:
- 在PSM之后,HF患者在索引录取期间死亡率 (OR2.79),严重出血 (OR1.26) 和急性损伤 (AKI) (OR2.11) 的几率更高.
- 死亡率 (OR 1.45),重大出血 (OR 1.53) 和AKI (OR 2.24) 在30天的HF患者再入院后仍然显著较高.
- 在LAAO后的HF患者中,没有观察到心周溢出,吸管或中风的显著增加.
结论:
- 与非HF患者相比,HF患者的LAAO与输出,吸管或中风的周围程序风险增加无关.
- 接受LAAO治疗的HF患者的死亡率,严重出血率和AKI率略高.
- 需要进一步的研究,以了解LAAO后HF患者的长期中风风险.
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