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相关概念视频

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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
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The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling.
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...
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具有极轻物质合的单分子敏感三维原子异构结构

Yi-Jui Yeh1,2, Shao-Yu Chen2, Wesley Wei-Wen Hsiao1

  • 1Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.

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概括

用等离子体辅助的表可以实现超敏感单分子检测的新型三维异构 (3DHS). 这种可扩展的纳米制造方法为先进的生物传感和纳米电子应用提供了一个新的平台.

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科学领域:

  • 材料科学
  • 纳米技术
  • 生物医学工程

背景情况:

  • 三维异构 (3DHS) 对于各种应用至关重要,但面临着制造方面的挑战.
  • 传统方法的控制能力不佳,成本高昂,使用危险的化学物质.

研究的目的:

  • 设计一个金属有机3DHS与增强的光物质交互快速单分子传感.
  • 为先进材料开发可扩展和具有成本效益的纳米制造方法.

主要方法:

  • 采用等离子体辅助表 (PAE) 来实现金银核心外纳米颗粒 (AuAgCSNPs) 的微等离子体纳米制造.
  • 在灵活的基板上在环境条件下设计的等离子活性3DHS.

主要成果:

  • 实现了基于AuAgCSNP的3DHS的精确工程,具有特殊的拉曼增强.
  • 通过表面增强的拉曼散射 (SERS) 证明了SARS-CoV-2尖端蛋白的单分子检测.

结论:

  • 开发了一种可扩展的环境条件等离子体制造方法,用于厘米级的SERS-主动3DHS.
  • 这项技术为下一代生物传感,纳米电子和纳米催化开辟了新的途径.