最近在心血管疾病中应用多元形和离子学方面的进展
Yan Zhang1, Zaicheng Zhang2, Hengtao Li2
1Shenzhen Key Laboratory of Marine Bioresources and Ecology, Brain Disease and Big Data Research Institute, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province 518055, PR China; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province 518055, PR China.
元素失衡,特别是铜,有毒金属,和,与心血管疾病有关. 离子学揭示了用于疾病诊断和预后的独特离子模式.
科学领域:
- 生物化学 生物化学
- 人体生理学 人体生理学
- 环境健康 环境健康
背景情况:
- 微量元素和矿物质对人类健康至关重要.
- 这些元素的不平衡与各种疾病有关.
- 多元元素分析和离子学是研究元素变化的先进技术.
研究的目的:
- 审查最近在多元元素和离子学分析方面的进展.
- 为了研究心血管疾病的元素概况.
- 了解元素dyshomeostasis在疾病发展中的作用.
主要方法:
- 综述了多元元素和ionomic分析的最新研究.
- 对人类生物样本 (生物液体,头发) 的分析.
- 应用高通量元素分析技术和生物信息学.
主要成果:
- 在心血管疾病中观察到的明显和动态的离子含量模式.
- 铜,有毒金属,和的不平衡被确定为重大风险因素.
- 患者样本中的独特离子分布可以作为疾病指标.
结论:
- 多元元素分析和离子学加深了对心血管疾病中的元素双相适应的理解.
- 这些技术有助于发现新的诊断和预后标志物.
- 元素分析提供了对疾病机制和潜在干预措施的见解.
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