对儿童暴露于有毒元素和神经认知发育的系统审查
Tingyi Guo1, Moslem Lari Najafi2, Junmei Zhang1
1Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Ecotoxicology and environmental safety
|February 11, 2025
概括
对潜在有毒元素 (PTEs) 的暴露与儿童的认知缺陷有关. 本综述综合了关于PTE和儿童神经发育的研究,强调了潜在的风险.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
背景情况:
- 暴露于潜在有毒元素 (PTEs) 对儿童神经发育是令人担忧的.
- 将PTE与神经发育障碍和认知缺陷联系在一起的机制需要进一步了解.
研究的目的:
- 系统地审查和巩固关于PTE暴露与儿童神经认知发育之间的关联的研究.
主要方法:
- 在Web of Science和PubMed的系统文献搜索,截至2024年4月15日.
- 遵守MOOSE指南和使用Gascon等. (2016) 用于研究评估.
- 包括15项涉及8391名参与者的研究.
主要成果:
- 研究结果表明,PTE如,,和化物可能会对儿童的神经认知发育产生不利影响.
- 相关的缺陷包括较低的智商,注意力,记忆问题和行为问题.
- 确定的局限性包括研究设计,地理差异和进一步研究的需要.
结论:
- 暴露于PTE对儿童的神经认知发育构成潜在风险.
- 建议进一步研究纵向设计,多样化的生物标志物和更广泛的地理范围.
- 了解累积效应和暴露途径至关重要.
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