在MS常规临床护理中使用哪种类型的PROM:PROMIS CAT问卷的有效性
Heleen Beckerman1, Isaline C J M Eijssen1, Roos Walraven2
1MS Center Amsterdam, Rehabilitation Medicine, Amsterdam UMC Location Vrije Universiteit, Amsterdam, the Netherlands; Societal Participation and Health, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Multiple sclerosis and related disorders
|February 11, 2025
概括
患者报告结果测量信息系统®计算机自适应测试 (PROMIS CATs) 对多发性硬化症 (MS) 患者显示出强大的构造有效性. 这些PROMIS CAT需要的物品比传统的PROM少得多,提高了MS护理的效率.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 健康 结果 研究 研究 结果
背景情况:
- 多发性硬化症 (MS) 护理正在向以患者为中心的方法过渡.
- 患者报告的结果指标 (PROM) 对于制定个性化治疗目标和促进患者提供者沟通至关重要.
- 赋权患者在临床环境中积极贡献他们的价值观和需求.
研究的目的:
- 在MS门诊患者中评估七个患者报告结果测量信息系统®计算机自适应测试 (PROMIS CATs) 的构造有效性.
- 为了评估包括焦虑,抑郁,疼痛干扰,疲劳,睡眠障碍,身体功能和社会参与在内的各个领域的PROMIS CAT.
- 为了比较PROMIS CATs所需的项目数量与MS研究和医疗保健中的传统PROMs.
主要方法:
- 一项横截面研究分析了498名成年多发性硬化症门诊患者的数据.
- 使用预定义的斯皮尔曼相关性与已建立的仪器 (HADS,MSWS-12,MSIS29,EQ5D,CIS20r,AMSQ-sf) 测试了PROMIS CATs的构造有效性.
- 如果超过75%的假设被满足,则验证有效性,对相应的 (≥0.70) 和相关 (≥0.50) 构造具有特定的相关值.
主要成果:
- 所有七个PROMIS CAT在MS门诊患者中都显示出足够的构造有效性,其中94%的假设得到证实.
- 与相应结构的相关性通常很高 (≥0.70),抑郁症的相关性为0.68.
- PROMIS CAT 平均每个域只需要四个项目,而传统 PROM 则需要78个项目.
结论:
- 七个评估的PROMIS CAT表现出足够的构造有效性,可用于MS门诊患者群体.
- 与传统的PROM相比,PROMIS CAT在MS医疗保健和研究中提供了一个更有效的评估工具.
- 这些发现支持将PROMIS CAT集成到多发性硬化症中,以加强以患者为中心的护理.
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