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Updated: Jul 9, 2026

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons
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在对人类成熟大脑衍生神经营养因子的神经保护中应用mRNA技术

Liang Wang1, Fengjuan Su1, Heng Huang1

  • 1Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, Guangzhou 510080, China; National Key Clinical Department and Key Discipline of Neurology, Guangzhou 510080, China.

Tissue & cell
|February 11, 2025
PubMed
概括

使者RNA (mRNA) 技术可以提供人类成熟的大脑衍生神经营养因子 (hmBDNF) 来保护神经元. 优化的hmBDNFmRNA增强了分化的神经元细胞的存活率,显示了未来治疗的潜力.

关键词:
大脑衍生的神经营养因子成熟的人类BDNF神经元保护 神经元保护治疗疗法 治疗疗法它们是mRNARNA.

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An Improved Protocol to Purify and Directly Mono-Biotinylate Recombinant BDNF in a Tube for Cellular Trafficking Studies in Neurons

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