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Updated: May 28, 2025

Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension
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通过综合转录组分析和临床前研究,揭开AURKB作为肺高血压的潜在治疗点

Sarah-Eve Lemay1, Manon Mougin1, Mélanie Sauvaget1

  • 1Pulmonary Hypertension Research Group, Québec Heart and Lung Institute Research Centre, Québec City, QC, Canada.

Cell reports. Medicine
|February 11, 2025
PubMed
概括

光激酶B (AURKB) 抑制为肺动脉高血压 (PAH) 提供了一个有前途的新疗法策略. 在光滑肌肉细胞中准AURKB可以逆转PAH特征并改善疾病模型.

关键词:
在FOXM1中,我们可以看到FOXM1.极光酶 B 的作用发生线粒分裂 (mitosis).肺动脉高血压 肺动脉高血压右心室衰竭是什么意思衰老是一种老化.血管改造 血管改造 血管改造

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