移动沙子:揭示沙特阿拉伯呼吸道并发病症和真菌病原体的变化
Aiah M Khateb1, Fadwa S Alofi1, Mohammad A Alturkostani1
1From the Department of Clinical Laboratory Sciences (Khateb), Collage of Applied Medical Science, Taibah University, from King Fahd Medical Research Center (Khateb), King Abdulaziz University, Jeddah, from the Department Infectious Diseases (Khateb), King Fahad Hospital, Medina, from Infectious Diseases Department (Alofi) and from the Microbiology laboratory (Alturkostani, Almutairi), King Fahad Hospital, Al Madinah Al Munawwarah, Kingdom of Saudi Arabia.
呼吸道真菌感染 (RFI) 的流行率在十年内增加了12倍,Candida albicans是最常见的原因. 持续监测和改进的诊断对于管理这些不断增加的感染是必不可少的.
科学领域:
- 医学真菌学 医学真菌学
- 传染病 流行病学 流行病学
- 临床微生物学 临床微生物学
背景情况:
- 呼吸道真菌感染 (RFI) 越来越多地被认为是一个重大的健康问题.
- 发病率上升与不断增长的免疫受损人群,病毒感染和人口老龄化有关.
- 了解RFI的流行病学转变对于公共卫生至关重要.
研究的目的:
- 分析呼吸道真菌感染流行病学的趋势和变化.
- 为了确定常见的真菌病原体及其在麦地那的流行情况.
- 调查相关的并发症和耐药性模式.
主要方法:
- 追溯的横截面研究设计.
- 在2013年至2023年期间,从麦地那的法哈德国王医院收集的数据.
- 对真菌阳性呼吸道培养物的分析,包括支气管支气管洗和肺活检样本.
主要成果:
- 在研究期间观察到RFI患病率增加了12倍.
- 坎迪达阿尔比坎斯 (43%) 是主要的分离物,其次是坎迪达热带植物 (34%).
- 呼吸系统疾病和糖尿病是最常见的并发病;发现了一例对沃里康纳和康纳耐药的Candida glabrata.
结论:
- 虫 Candida albicans 是研究群体中 RFI 的主要病因病因.
- 加强监测,诊断和有针对性的干预措施至关重要.
- 增加研究和医疗保健专业教育是必要的,以打击新出现的真菌威胁.
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