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对整个监狱重复进行型肝炎检测的影响的前性评估

Naw April Phaw¹, Aung Min Thant², Craig Thompson³

¹Liver Unit and NIHR Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.

BMJ open gastroenterology

|February 11, 2025

概括

在监狱中,可能不需要重复的高强度检测和治疗 (HITT) 程序来检测型肝炎病毒 (HCV). 优化常规接收测试对于维持HCV微分泌更为有效.

科学领域:

肝病学肝病学是一种肝病学.
传染性疾病传染性疾病
惩戒设施中的公共卫生.

背景情况:

慢性型肝炎病毒 (HCV) 感染是惩戒设施中严重的公共卫生问题.
虽然建议进行普遍的HCV检测,但低于最佳的接受率需要策略来识别和治疗错过的感染.
高强度检测和治疗 (HITT) 计划旨在在监狱内进行快速,全面的HCV查.

研究的目的:

在女性监狱首次HITT发生4年后,评估后续HITT计划的有效性.
评估需要重复的HITT与优化持续的接收测试对HCV微分泌的需求.

主要方法:

在一个女性监狱进行了前性观察研究,比较了2020年和2024年的两个HITT.
在HITTs.Tests之间的4年间隔中分析了接收测试结果.
评估了活跃HCV感染的患病率和治疗成功率.

主要成果:

在2020年和2024年,HITT实现了高居民测试覆盖率 (超过95%).
新诊断的HCV感染的患病率显著下降,从2020年的6.6%降至2024年的0.3%.
在2020年至2023年期间,接收检测覆盖率从83%提高到95%,其中81%的活跃感染成功治疗.

结论:

4年后的一次随访HITT在以前高患病率的监狱中发现了最小的活跃HCV感染 (0.3%).
目前正在进行的接收测试和治疗计划在控制HCV方面表现出高效.
资源应该优先优化接收测试策略,而不是重复的HITT,以在监狱中持续的HCV微排泄.

关键词:

抗病毒疗法抗病毒治疗医疗服务研究研究肝炎C型肝炎肝炎C型肝炎

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