关节功能的挑性测试与便失禁的症状和亚型相关
Alexander O'Connor1,2, Donghua Liao3, Matthew Davenport4,2
1Faculty of Biology, Medicine and Health, The University of Manchester and Manchester Academic Health Sciences Centre Manchester, Manchester, UK alexander.oconnor@manchester.ac.uk.
便失禁 (FI),功能光成像探针 (FLIP) 和声反射计 (AAR) 的挑性测试与症状严重程度的相关性比高分辨率直肠测量 (HRAM) 更好. 这些发现表明,FLIP和AAR可以指导FI管理.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 盆地底疾病 盆地底疾病
- 诊断成像 诊断成像 诊断成像
背景情况:
- 高分辨率阳门测量 (HRAM) 是检查便失禁 (FI) 的标准.
- 功能光成像探针 (FLIP) 和声反射计 (AAR) 正在成为FI评估的潜在替代方案.
- 这三种方法在FI症状和亚型方面缺乏直接比较.
研究的目的:
- 为了比较HRAM,FLIP和AAR与便失禁严重程度和亚型的相关性.
- 评估挑性测试 (FLIP和AAR) 与已建立的HRAM在诊断FI时的有用性.
主要方法:
- 进行了一项前性观察性研究,涉及40名FI患者.
- 患者接受了随机的HRAM,FLIP和AAR评估.
- 使用Vaizey评分测量FI严重程度,使用曼彻斯特健康问卷测量生活质量.
主要成果:
- 与HRAM不同的是,FLIP和AAR与FI症状严重程度 (Vaizey得分) 有显著的相关性.
- 被动FI亚型在所有三种模式 (HRAM,FLIP,AAR) 中都显示出较低的静止压力.
- 没有发现任何方法的参数与生活质量得分之间的相关性.
结论:
- 功能性光成像探针 (FLIP) 和声反射计 (AAR) 与便失禁症状严重性相比,与高分辨率直肠计量 (HRAM) 相比显示出更好的相关性.
- 这些挑性的测试有望指导便失禁的临床管理.
- 需要进一步的前性研究来验证这些发现,并将FLIP和AAR整合到常规FI诊断中.
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