关于预防和管理ICU狂妄症干预措施的元综述的议定书
Katherine Louise Jones1, Burak Kundakci1, Andrew Booth1
1The University of Sheffield, Sheffield, England, UK.
BMJ open
|February 11, 2025
概括
重症监护室 (ICU) 的妄想影响了许多患者,增加了成本和死亡率. 本元综述对干预措施的证据进行了映射,以指导新的预防和管理战略.
科学领域:
- 临界护理医学 临界护理医学
- 神经科学是一个神经科学.
- 证据综合 证据综合
背景情况:
- 重症监护室 (ICU) 痴呆症是重症患者常见的并发症,影响到70%的入院患者.
- 集中治疗室妄想导致长时间住院,增加医疗费用,增加死亡率和长期认知障碍.
- 目前的预防和管理策略涉及药理学和非药理学方法,但最佳组件仍然不清楚.
研究的目的:
- 系统地绘制ICU Delirium干预随机对照试验 (RCT) 审查和元分析的证据的数量和确定性.
- 为设计一个多组件干预措施的设计提供信息,以预防和管理ICU狂妄症.
主要方法:
- 在多个数据库 (MEDLINE,Embase,Cochrane,Scopus,CINAHL,PsycINFO,Web of Science,Epistemonikos) 进行了全面的系统搜索,截至2023年9月.
- 包括专注于重症成人 (≥18岁) 和任何药理或非药理ICU Delirium干预的研究.
- 对药理干预的RCT的审查包括在内;对非药理干预的RCT,准实验和队列研究的审查. 通过使用定量数据描述来综合发现.
主要成果:
- 该部分将在研究完成后填写.
结论:
- 这一元综述将全面概述ICU Delirium干预现有证据库.
- 这些发现将指导基于证据的多元组件策略的制定,以改善ICU患者的治疗结果.
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