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Updated: May 28, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
10:01

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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用质谱测量对亲和性毛细电泳的杂化,用于研究联体蛋白相互作用: - - 甲基酸甲基缓冲剂和基于多多巴胺的涂层作为关键资产

Clara Davoine1, Marianne Fillet1

  • 1Laboratory for the Analysis of Medicines (LAM), Department of Pharmacy, CIRM, University of Liege, Avenue Hippocrate 15, B36 Tour 4 +3, 4000 Liège, Belgium.

Analytical chemistry
|February 11, 2025
PubMed
概括

这项研究引入了在生理条件下用于亲和毛细血管电泳质谱 (ACE-MS) 的新型缓冲和涂层解决方案. 这些进步改善了用于药物发现的蛋白质分析,提高了准确性和效率.

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