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Updated: May 28, 2025

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青少年的低FODMAP饮食功能性腹部在非指导的设置:一个前性的多中心队列研究研究

Robyn Rexwinkel^1,2,3, Nicolaas Koen Vermeijden^4,5,6,7, Judith Zeevenhooven¹

¹Emma's Children Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Pediatric Gastroenterology, Hepatology and Nutrition, Room C2-312, PO Box 22700, 1100 DD, Amsterdam, The Netherlands.

European journal of pediatrics

|February 11, 2025

概括

低FODMAP饮食在没有营养学家指导的情况下,在IBS或FAP-NOS的青少年中表现出有限的成功. 大约30%的IBS患者和17%的FAP-NOS患者获得了治疗成功.

科学领域:

儿科胃肠病学儿科胃肠病学
饮食干预饮食干预
功能性胃肠道疾病功能性胃肠道疾病

背景情况:

刺激性肠综合征 (IBS) 和功能性腹痛 - 没有其他规范 (FAP-NOS) 在儿童中很普遍,显著影响他们的生活质量.
低发酵的寡糖,分糖,单糖和多 (FODMAPs) 饮食对成年IBS有效,但其在儿童群体中的有效性不太清楚.
低FODMAP饮食在临床实践中经常在没有专业营养师指导的情况下实施,与受控研究环境不同.

研究的目的:

评估低FODMAP饮食对被诊断患有IBS或FAP-NOS的青少年的有效性.
在没有营养学家支持的情况下,在现实临床环境中评估饮食的有效性.
根据显著减少腹痛强度来确定治疗成功率.

主要方法:

一项前性多中心队列研究,涉及325名12至18岁的IBS或FAP-NOS患者.
参与者获得了关于低FODMAP饮食的教育材料,并被告知在不咨询营养师的情况下,在四周内修改其摄入量.
治疗成功被定义为≥30%的腹痛强度降低,而足够的症状缓解是次要结果.

主要成果:

在四周后,24.9%的参与者获得了整体治疗成功.
与FAP-NOS (16.8%) 相比,患有IBS的青少年的成功率更高 (29.3%).
观察到腹部疼痛强度,每日胀气和浮气明显减少;不良事件是轻微的和不频繁的.

结论:

低FODMAP饮食在没有营养师指导的情况下实施时,在IBS的青少年中表现出中等的成功,在FAP-NOS的青少年中表现出较低的成功.
这些发现表明,无指导的低FODMAP饮食可能不是儿科IBS和FAP-NOS的最佳一线治疗方法.
进一步的研究可能是有必要的,以探索最佳的饮食策略和专业指导在儿科功能性胃肠道疾病中的作用.

关键词:

孩子孩子孩子孩子这就是FODMAP.功能性腹痛障碍功能性腹痛障碍

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