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核磁共振成像纹理分析对核磁共振指导肝活检复杂率的影响

Jakob Leonhardi¹, Maike Niebur¹, Anne-Kathrin Höhn²

¹Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Journal of imaging informatics in medicine

|February 11, 2025

概括

磁共振成像 (MRI) 纹理特征可以预测肝脏手术中的出血风险和活检成功. 这些定量成像参数有助于在皮肤MRI导向肝活检前识别高风险患者.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
在瘤学瘤学.

背景情况:

从MRI获得的定量成像参数,称为纹理特征,显示潜在的临床关联.
这些纹理特征的预后价值,用于预测活检后出血并发症和皮肤MRI导向肝脏活检的成功率,仍未得到充分研究.

研究的目的:

调查MRI衍生的纹理特征与介入后出血并发症和活检成功率的关联.
为了识别潜在的成像生物标志物,用于通过皮肤进行MRI指导肝活检的患者的风险分层.

主要方法:

对79名接受皮肤MRI指导肝活检的患者的分析.
从目标病变的规划序列中提取MRI纹理特征.
统计分析包括曼·惠特尼U测试,费舍尔精确测试和多变量回归模型,以将纹理特征与临床结果 (出血,活检成功) 相对应.

主要成果:

多个MRI纹理特征在患有和没有活检后出血的患者之间有显著差异.
纹理特征GrVariance显示了与出血并发症相关的最高统计意义 (p=0.007).
特定的纹理特征,S(1,1) DifEntrp和S(0,4) DifEntrp,与不成功的活检结果显著相关 (p=0.022和p=0.021,分别).

结论:

目标肝脏病变的MRI纹理特征与出血并发症和负面活检结果有关.
这些定量成像参数可能有助于在手术前识别患有不良事件或活检失败风险的患者.
需要进一步的研究来验证这些发现,并将纹理分析纳入临床实践,以提高患者安全和程序成功.

关键词:

发生出血发生出血肝脏活检活检是什么意思这就是为什么MRI是MRI.无线电学 (Radiomics) 是一种无线电学.质感分析质感分析

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