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Updated: May 28, 2025

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TGF-β1诱导粘膜母细胞基因,并通过IL-3/ERK1/2轴负面调节

Steffen K Meurer1, Gina Bronneberg2, Christian Penners3

  • 1Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany. smeurer@ukaachen.de.

Cell communication and signaling : CCS
|February 11, 2025
PubMed
概括

转化生长因子-β1 (TGF-β1) 促进巨细胞分化和粘膜基因表达. 干白素-3 (IL-3) 和细胞外信号调节激酶 (ERK1/2) 抵消这些影响,平衡增殖和分化.

关键词:
在ERK1/2中.在IL-3中,IL-3被认为是IL-3.一个MCPT1一个MCPT1巨细胞分化分化这些SMAD是SMAD.的TGF-β受体.的TGF-β信号传输.

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