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Updated: May 28, 2025

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
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Published on: July 29, 2022

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α-Synuclein在帕金森病中作为抗原和辅助剂协调Th17反应

Emi Furusawa-Nishii1, Bataa Solongo1, Kou Rai1

  • 1Department of Immunology, Juntendo University, Faculty of Medicine, Bunkyo-ku, Tokyo, Japan.

Journal of neuroinflammation
|February 11, 2025
PubMed
概括

针对化α-synuclein (pS129) 的T细胞与帕金森病 (PD) 的进展有关. 具体来说,Th17细胞反应与PD严重程度相关,由树突细胞通过TLR4-XBP1s-IL-23信号传递驱动.

关键词:
它们有IL-23和IL-23.在TLR 4中,有4个TLR.剪接的 X 盒结合蛋白质.综核蛋白异常症 (synucleinopathy) 是一种同核蛋白异常症.α-同核素特异性T细胞

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