对患有婴儿维生素B12缺乏症的儿童的身体成分的研究
Viresh Vohra1, Harvinder Kaur1, Savita Verma Attri1
1Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Journal of paediatrics and child health
|February 11, 2025
概括
严重的婴儿维生素B12缺乏 (ITS) 会阻碍生长和发育,导致和贫血. 它还导致异常的脂质样本,增加长期心血管风险在受影响的儿童.
科学领域:
- 儿童营养学 儿童营养学
- 发育儿科 发育儿科
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 婴儿震综合征 (ITS),也被称为神经皮肤婴儿维生素B12缺乏综合征 (NIBS),表现为震,发育迟缓,贫血和多颜色.
- 维生素B12缺乏是儿童早期发育的一个关键问题.
研究的目的:
- 评估被诊断患有婴儿震综合征 (ITS) 的婴儿的身体组成和血清脂质概况.
- 了解维生素B12缺乏对幼儿的代谢和发育的影响.
主要方法:
- 包括患有临床ITS诊断的两岁以下儿童.
- 收集了饮食史,发育里程碑,人体测量数据和血液测试 (B12,同类氨酸,脂质,血液计数).
主要成果:
- 分析了31名儿童 (平均年龄为13个月);大多数来自较低的社会经济背景.
- 观察到显著的发育迟缓 (DQ < 70),小头症 (35.4%),以及近乎普遍的贫血.
- 患有ITS的儿童表现出较低的脂肪和无脂肪质量,以及异常的脂质样本 (高甘油三,低HDL,高LDL),表明了亲动脉动脉的状态.
结论:
- 严重的婴儿维生素B12缺乏严重影响头部生长,发育和身体组成.
- 在ITS中异常的脂质概况表明潜在的长期心血管风险需要进一步调查.
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