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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

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Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
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Drug Therapy01:28

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
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Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

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Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
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帕利皮里顿诱导的甲状腺功能低下症:一个病例报告

Mohammed A Mohammed1, Abdullah Almarzogi2, Anas Ibn Auf3

  • 1Mohammed, Erada and mental health complex, Taif, Saudi Arabia.

Psychopharmacology bulletin
|February 12, 2025
PubMed
概括

帕利佩里是一种抗精神病药物,可能导致甲状腺功能低下. 监测甲状腺功能 (TSH,FT4) 在接受帕利佩里治疗的精神分裂症患者中至关重要,以检测和管理潜在的内分泌副作用.

关键词:
抗精神病药物 抗精神病药物甲状腺功能低下症 甲状腺功能低下症帕利皮里多尼是什么?精神分裂症是一种精神分裂症.有关副作用的副作用是什么?

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科学领域:

  • 内分泌学 在内分泌学.
  • 精神病学是一个精神病学.
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 抗精神病药物与甲状腺功能障碍有关,特别是亚临床甲状腺功能低下症.
  • 第二代抗精神病药物,如帕利佩里,需要仔细的内分泌监测.

研究的目的:

  • 在精神分裂症患者中报告与帕利佩里治疗相关的甲状腺功能低下病例.
  • 为了强调在帕利皮里治疗期间甲状腺功能监测的重要性.

主要方法:

  • 一个31岁的男性患有精神分裂症的病例报告.
  • 短期使用帕利佩里治疗.
  • 在随访期间进行常规甲状腺功能测试 (TSH,FT4).

主要成果:

  • 帕利佩里治疗与甲状腺刺激激素 (TSH) 的升高和自由甲状腺素 (FT4) 水平的降低有关.
  • 甲状腺功能的改变表明了潜在的甲状腺功能低下症的联系.

结论:

  • 持续监测甲状腺功能对于服用帕利佩里的患者至关重要.
  • 提高医疗保健提供者对帕利佩里内分泌作用的认识,可以改善患者的治疗结果.