患有艾滋病毒的男性和女性中抑郁症状和左心室透气功能障碍
Claudia Martinez1, Nel Jason Haw2, Violeta J Rodriguez3
1University of Miami Miller School of Medicine, Florida, USA.
概括
在艾滋病毒感染或不感染的成年人中,抑郁症状与左心室扩张功能障碍 (LVDD) 并没有显著联系. 需要进一步的研究来理解这种关系在现代艾滋病毒治疗的背景下.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- 抑郁症状在艾滋病毒感染的成年人中很常见,并且与心血管疾病有关.
- 左心室扩张功能障碍 (LVDD) 是一种可以影响心脏功能的心脏疾病.
研究的目的:
- 调查艾滋病毒感染者和未感染者的男性和女性抑郁症状和LVDD之间的关联.
主要方法:
- 从多中心艾滋病队列研究 (MACS) 和妇女机构间艾滋病毒研究 (WIHS) 的数据进行横截面分析.
- 参与者已经控制了艾滋病毒 (CD4>350,病毒载量<499).
- 用抗逆转录病毒疗法 (CHART) 标准来评估LVDD;统计模型根据多个因素进行调整.
主要成果:
- 该研究包括874名男性和1,191名女性;22.5%的人患有LVDD,30.8%的人报告抑郁症状.
- 总体而言,抑郁症状与LVDD没有显著的关联.
- 单个LVDD组件与抑郁症之间的关联小到中,但一般不显著.
结论:
- 该研究没有发现艾滋病毒感染者接受联合抗逆转录病毒疗法的抑郁症状和LVDD之间的显著关联.
- 需要进一步的研究来探索当前治疗时代的这种关系.
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