24小时门诊血压监测在开放角度的玻璃眼疑似患者:一个横截面描述性研究
Mahesh Bharathi1, Subashini Kaliaperumal2, Sandhiya Selvarajan3
1Glaucoma Consultant, Ahalia Eye Hospital, Palakkad, India.
Romanian journal of ophthalmology
|February 12, 2025
概括
青光眼疑似患者改变了24小时血压模式,并减少了视网膜神经纤维层 (RNFL) 的厚度,特别是在非浸泡者中. 夜间血压降低与视神经头部损伤有关,表明潜在的全身血管作用.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 与健康个体相比,疑似青光眼患者经常表现出明显的24小时血压 (BP) 模式.
- 在疑似青光眼患者中,血压变化和视网膜神经纤维层 (RNFL) 厚度之间的关系需要进一步调查.
研究的目的:
- 为了比较青光眼疑似患者与健康受试者的24小时血压模式.
- 为了评估视网膜神经纤维层 (RNFL) 厚度与夜间血压下降状态的关系,在青光眼怀疑患者中.
主要方法:
- 100名青光眼疑似患者和100名对照患者接受了24小时的门诊血压监测.
- 视网膜神经纤维层 (RNFL) 的厚度是使用光学一致性断层扫描 (OCT) 来测量的.
- 根据夜间平均动脉压降低,被试被分为浸泡者和非浸泡者.
主要成果:
- 与对照人群相比,可疑患有青光眼的患者在白天和夜间的缩血压显著降低,腹缩血压更高.
- 在被怀疑患有青光眼的患者中,露面浸泡者与非浸泡者和浸泡者相比显示出显著的RNFL稀释.
- 在夜间血压下降和平均RNFL厚度 (r = -0.396,p < 0.001) 之间发现了负相关性.
结论:
- 改变的24小时血压模式在青光眼疑似患者中是显而易见的.
- 夜间血压降低与结构性视神经损伤有关,这表明系统性血管对玻璃眼病进展的贡献.
- 门诊血压监测可能有助于识别有更高进展风险的青光眼疑似患者.
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