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Updated: May 28, 2025

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代谢功能障碍相关的脂肪性肝病中的微RNA:临床研究的系统性审查

Eleni Antoniou1, Evangelos Oikonomou2, Panagiotis Theofilis3

  • 1Cardiology Department, General Hospital of Corinthos, Greece.

MicroRNA (Shariqah, United Arab Emirates)
|February 12, 2025
PubMed
概括

微RNAs (miRs) 作为代谢功能障碍相关的性肝病 (MASLD) 的生物标志物具有前景. 特定的miR与MASLD严重程度,纤维化和肝细胞癌 (HCC) 有关,有助于诊断和预后.

关键词:
非酒精性脂肪性肝病是非酒精性脂肪性肝病.纤维化 纤维化与代谢功能障碍相关的脂肪性肝病.这就是为什么 miRR 是 miR.没有编码的RNA.蒸汽症是一种蒸汽症.

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
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