一项描述性,回顾性单中心研究,针对COVID-19的重症监护病房患者的空气泄漏综合征
Alice Löwing Jensen1, Jacob Litorell1, Jonathan Grip2,3
1Department of Anaesthesia and Intensive Care, Södersjukhuset, Stockholm, Sweden.
Acta anaesthesiologica Scandinavica
|February 12, 2025
概括
12%的COVID-19重症监护室 (ICU) 患者患有空气泄漏综合征,这是一个严重的并发症. 肺中介是最常见的类型,空气泄漏综合征与较高的死亡率有关.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 急性呼吸衰竭是ICU中的COVID-19患者的主要关注点.
- 肺部保护策略对于预防空气泄漏综合征等并发症至关重要.
- 这项研究调查了瑞典ICU的COVID-19患者的空气泄漏综合征.
研究的目的:
- 为了确定COVID-19ICU患者中空气泄漏综合征的患病率,类型和时间.
- 为了确定与空气泄漏综合征相关的因素.
- 分析与空气泄漏综合征相关的患者结果,包括90天死亡率.
主要方法:
- 在2020年3月至2021年6月期间接受ICU治疗的669名成年COVID-19患者的回顾性研究.
- 分析空气泄漏综合征的表现,相对于ICU入院和通风的时间,以及相关的风险因素.
- 在有空气泄漏综合征和没有空气泄漏综合征的患者中,90天死亡率的比较.
主要成果:
- 12% (81/669) 的患者被诊断出患有空气泄漏综合征.
- 肺中症 (72%) 比肺胸部 (53%) 更常见.
- 空气泄漏综合征发生在ICU入院后的中位数为14天和侵入性通风后的12天.
- 与风险增加相关的因素包括基线肺病,较低的BMI,晚期的流行病入院和侵入性通风.
- 患有空气泄漏综合征 (46%) 的患者的90天死亡率高于没有空气泄漏综合征的患者 (26%).
结论:
- 空气泄漏综合征影响了12%的COVID-19重症监护室患者,肺中是最常见的表现.
- 这些发现表明,在COVID-19相关的空气泄漏综合征中,可能存在不同的病理生理学或催化剂机制.
- 需要进一步的研究,以了解这些机制与其他关键呼吸系统疾病相比.
相关概念视频
Endoscopic Studies II: Thoracocentesis
195
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
195
Acute Respiratory Failure-V
117
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
117


