在秘鲁的三个青少年拘留中心积极寻找结核病
Judith Jimenez1, Ana Karina Millones1, Daniela Puma1
1Socios En Salud Sucursal Perú. Lima, Perú.
Revista peruana de medicina experimental y salud publica
|February 12, 2025
概括
在少年拘留中心的活跃结核病 (TB) 查发现病例比一般人口多10倍. 大多数结核病病例无症状,这凸显了针对脆弱年轻人进行查的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 医学诊断 医学诊断 医学诊断
背景情况:
- 结核病 (TB) 仍然是全球主要的传染性死亡原因,存在显著的检测差距.
- 弱势群体,包括少年监狱中的弱势群体,需要针对性地积极寻找结核病的战略.
- 目前的查方法可能无法在这些环境中充分识别无症状个体的结核病.
研究的目的:
- 通过在拘留中心的青少年和青少年中使用积极的搜索策略来确定结核病 (TB) 的流行率.
- 评估一个集胸部X射线,人工智能,GeneXpert测试和临床评估的活跃搜索算法的有效性.
- 将这一群体中的结核病检测率与一般人口进行比较.
主要方法:
- 在三个青少年拘留中心对640人进行了查,使用多面性主动搜索算法.
- 利用胸部X射线与人工智能辅助自动读取,GeneXpert Ultra MTB/RIF分子测试和临床评估.
- 收集了关于异常胸部X射线,呼吸系统症状和抗逆转录病毒治疗状态的数据.
主要成果:
- 在查的人口中发现了8例结核病 (8.5%).
- 活跃搜索查率为每10万人中1250人,比一般人口率高10倍.
- 在确诊的结核病例中,75%无症状,42.8%患有抗利芬素结核病 (RR-TB).
结论:
- 青少年拘留中心的活性结核病查在检测病例方面非常有效,包括无症状个体.
- 青少年拘留中心应优先考虑系统的结核病查计划.
- 实施创新的查方法可以改善早期病例检测,治疗结果,并减少结核病传播.
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