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Updated: May 28, 2025

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
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Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

Published on: November 11, 2016

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对HCA1,HCA2和HCA3的激活机制的洞察

Jiening Wang1, Yuxia Qian2, Zhen Han2

  • 1State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China.

Journal of medicinal chemistry
|February 12, 2025
PubMed
概括

氧碳酸受体 (HCAs) 参与能量代谢. 这项研究揭示了它们的结构,揭示了连接体结合和激活的机制,特别是HCA1,这是脂解治疗的潜在目标.

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