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相关概念视频

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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相关实验视频

Updated: May 28, 2025

Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
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介酶干/干细胞微封装用于细胞治疗.

Sharaf Eldeen M Abbas1, Ghada Maged2, Hongjun Wang3,4

  • 1Department of Prosthodontics, Faculty of Dentistry, Cairo University, Giza 12613, Egypt.

Cells
|February 12, 2025
PubMed
概括

微封装保护介质干细胞/干细胞 (MSCs) 免受免疫排斥,改善存活率和向分娩. 这种细胞治疗策略增强了细胞相互作用,并显示出对体内应用的希望.

关键词:
多国中心的MSCs.生物材料是一种生物材料.细胞治疗疗法细胞治疗疗法介酶干细胞/介酶干细胞.微装封装是一种微装封装.

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科学领域:

  • 生物技术和再生医学 生物技术和再生医学
  • 细胞疗法和组织工程

背景情况:

  • 介质细胞干/干细胞 (MSCs) 面临着因免疫排斥而在体内治疗使用的挑战.
  • 细胞微封装提供了一个解决方案,通过在半透膜中屏蔽MSC.

研究的目的:

  • 审查用于微封装MSC的材料和技术.
  • 讨论最近在细胞治疗中封装的MSC的进展,好处,缺点和体内翻译.

主要方法:

  • 讨论了一些流行的微封装材料:酸盐,原和纤维素.
  • 突出了常见的技术:空气喷射挤出,微流体和乳液.
  • 基于微囊大小和材料兼容性的方法进行比较.

主要成果:

  • 微封装可以提高MSC的存活率和输注后的移植.
  • 在3D环境中实现有针对性的交付和改进的细胞相互作用.
  • 不同的材料和技术产生不同的微囊特性.

结论:

  • 微封装是克服体内MSC实施障碍的关键策略.
  • 封装的MSC显示出更好的治疗潜力和体内翻译能力.
  • 对材料和技术的进一步研究可以优化细胞治疗结果.