在波兰进行胃肠病变内镜全厚切除的多中心分析
Pawel Rogalski1, Wojciech Korcz2, Nastazja Dagny Pilonis2,3,4
1Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, Poland.
Scandinavian journal of gastroenterology
|February 12, 2025
概括
内镜全厚切除 (EFTR) 是一种安全有效的技术,用于去除胃肠病变. 这项研究显示EFTR在治疗困难的腺瘤,腺癌和亚皮质病变方面的成功率很高.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 在瘤学瘤学.
背景情况:
- 内镜全厚切除 (EFTR) 是一种用于消化道病变的创新技术.
- 这种方法允许在消化道中进行表面和亚皮质病变的非暴露切除.
研究的目的:
- 评估EFTR在胃肠切除和结直肠切除方面的有效性和安全性.
- 评估与EFTR相关的R0切除率和不良事件.
主要方法:
- 一项回顾性多中心研究分析了来自波兰6个中心的105次连续EFTR程序的数据.
- 患者被分为三个组:困难的腺瘤,腺癌或亚皮质病变 (SEL).
- 结果包括R0切除率和不良事件率,并进行了子组分析.
主要成果:
- 在96%的EFTR手术中取得了技术上的成功,在97%的技术上成功的情况下确认了R0切除.
- 治愈切除率很高,特别是在亚皮质病变 (88%) 和困难腺瘤 (100%) 中.
- 临床不良事件发生在11%的患者中,大多数是低度的 (Clavien-Dindo I-II).
结论:
- 内镜全厚切除 (EFTR) 证明了切除结直肠和胃肠病变的合理安全性和有效性.
- 对于许多胃肠道病变,EFTR为手术治疗提供了一个可行的替代方案.
- 这种技术对于困难的腺瘤和亚皮质病变特别有效.
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