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Updated: May 28, 2025

Subcellular Fractionation for ERK Activation Upon Mitochondrial-derived Peptide Treatment
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综合应激反应激酶的药理活性抑制了病理性线粒体分裂

Kelsey R Baron1, Samantha Oviedo1,2, Sophia Krasny1

  • 1Department of Molecular and Cellular Biology, The Scripps Research Institute, La Jolla, United States.

eLife
|February 12, 2025
PubMed
概括

激活综合应激反应 (ISR) 途径可以防止过度的线粒体分裂,这是许多神经退行性疾病的标志. 这种方法恢复了正常的线粒体形状和功能,提供了潜在的治疗策略.

关键词:
细胞生物学 细胞生物学人类 人类 人类 人类 人类 人类 人类综合应激反应综合应激反应线粒体碎片化的分裂线粒体形态的形态学这里是鼠标鼠标鼠标鼠标鼠标鼠标.压力信号的压力信号.

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