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Updated: May 25, 2026

Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors
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AZD8701,一种针对FOXP3mRNA的反意义寡核酸,作为单疗法和与杜尔瓦卢马布联合使用:在患有高级固体瘤的患者中进行I期试验

Lillian L Siu1, Sophie Postel-Vinay2, Rafael Villanueva-Vázquez3

  • 1Princess Margaret Cancer Centre, Toronto, Canada.

Clinical cancer research : an official journal of the American Association for Cancer Research
|February 12, 2025
PubMed
概括

这一第一阶段研究表明,针对FOXP3的抗意义寡核酸AZD8701在先进的固体瘤中具有临床可行性. 该疗法证明了可管理的安全性和成功地传递给瘤,支持进一步研究这种新型免疫疗法方法.

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