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Updated: May 28, 2025

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对SARS-CoV-2 Nsp4和宿主细胞ESCRT蛋白质的编排诱导了内细胞网膜的形态变化

Allison Kifer1, Franciso Pina1, Nicholas Codallos1

  • 1School of Biological Sciences, Department of Molecular Biology, NSB, University of California, San Diego, San Diego, CA 92093-0377.

Molecular biology of the cell
|February 12, 2025
PubMed
概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 非结构性蛋白4 (Nsp4) 单独诱导了病毒复制所必需的内分泌网膜 (ER) 重组. 这些变化涉及输送 (ESCRT) 途径的内体组分复合体,而不是规范的UPR或ERSU组件.

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