不安全的依恋对fMRI静止状态功能连接在多种药物使用障碍中的影响
Jürgen Fuchshuber1,2,3, Karl Koschutnig4, Andreas Fink4
1Department of Psychoanalysis and Psychotherapy, Medical University Vienna, Vienna, Austria.
PloS one
|February 12, 2025
概括
在多种药物使用障碍 (PUD) 患者中,不安全的成人依恋与更大的精神病理学有关. 这项研究发现,不安全的依恋与大脑网络中休息状态功能连接 (rs-FC) 的改变有关,这对于影响调节至关重要.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 成研究 研究成研究
背景情况:
- 不安全的成年人依恋与严重的精神病理学和改变的大脑连接性有关.
- 在多种药物使用障碍 (PUD) 中,对附着系统的静止状态功能连接 (rs-FC) 了解有限.
研究的目的:
- 在PUD患者中调查rs-FC.
- 检查成年人附着安全和rs-FC.之间的关系.
- 为了将依恋安全与心理症状相关联.
主要方法:
- 在33名PUD患者的2个时间点评估了rs-FC,使用ROI-to-ROI和种子-voxel分析.
- 成年人的依恋程度使用"亲密关系经验量表" (ECR-RD8) 来衡量.
- 不安全的依恋与抑郁症状 (ADS),特征焦虑 (STAI) 和一般精神病理学 (BSI-53) 相相关.
主要成果:
- 不安全的依恋与更高水平的特征焦虑,抑郁症状和一般精神病理学有关.
- 在不安全的附着和在默认模式网络的左侧顶部区域 (DMN LP) 和突出网络之间增加的rs-FC之间发现了时间稳定的关联.
- 在DMN LP和默认模式网络的中间部分之间观察到 rs-FC的减少.
结论:
- 研究结果强调了依恋安全与参与情感调节的大脑区域之间的关联.
- 这项研究提供了关于PUD中依恋的神经基础的见解.
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