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骨细胞连接素半通道和前列腺素E2的释放决定了骨髓中介质体细胞承诺

Jingruo Zhang1, Francisca M Acosta1, Xuewei Wang1

  • 1Department of Biochemistry and Structural Biology, University of Texas Health Science Center, San Antonio, TX 78229.

Proceedings of the National Academy of Sciences of the United States of America
|February 12, 2025
PubMed
概括

骨细胞连接素43 (Cx43) 半通道调节骨髓干细胞的命运. 破坏这些半通道会促进脂肪细胞的形成超过骨细胞,影响骨重塑.

关键词:
在 PGE2 信号传输中.骨髓中介细胞干细胞和祖先细胞.骨头改造 骨头改造 骨头改造连接 43 个半通道机械负荷是指机械负荷.

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