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新型银(I) 复合物与芬氨酸:对合成,光谱表征和生物活性的洞察

Lidia Zapała1, Ewa Ciszkowicz2, Małgorzata Kosińska-Pezda1

  • 1Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, Rzeszow University of Technology, Al. Powstańców Warszawy 6, 35-959 Rzeszów, Poland.

Journal of inorganic biochemistry
|February 12, 2025
PubMed
概括

六种新的含有N-phenylanthranilic,mefenamic和niflumic酸的银 (I) 复合物显示出对抗多药耐药Pseudomonas aeruginosa的潜在抗菌活性. 组合疗法和增强的膜透性表明改善了治疗应用,特别是用于局部皮肤使用.

关键词:
生物活动是生物活动.菲纳马特斯 (Fenamates) 是一种植物.银银复合体是一种复合体.频谱研究是指光谱研究.协同作用 协同作用 协同作用

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A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
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Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
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