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Updated: May 28, 2025

Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks
12:19

Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks

Published on: November 10, 2016

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在胰腺癌细胞中,MYH的淘汰创造了一个可利用的DNA修复漏洞

James Ephraums1, Janet Youkhana1, Aparna S Raina1

  • 1Pancreatic Cancer Translational Research Group, School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney; NSW 2052, Australia.

Neoplasia (New York, N.Y.)
|February 12, 2025
PubMed
概括

在胰腺癌 (PDAC) 中向MutY-Homolog (MYH) 诱导DNA损伤并使细胞对化疗敏感. 这种方法利用DNA修复漏洞对潜在的新PDAC治疗进行了利用.

关键词:
化学敏感化 化学敏感化修复DNA的修复DNA的修复氧化应激是一种氧化应激.胰腺癌是一种癌症.

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Immunofluorescence Microscopy of γH2AX and 53BP1 for Analyzing the Formation and Repair of DNA Double-strand Breaks10:47

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