儿童和青少年时期的早产相关发育智力障碍的全球流行和残疾
1Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Early human development
|February 12, 2025
概括
在早产 (CABP) 儿童中,早产相关发育智力障碍 (PDID) 的全球负担从1990年增加到2021年. 然而,在全球范围内,5岁以下儿童的负担已经下降,尽管社会人口统计指数较低的地区存在持续的挑战.
科学领域:
- 全球健康 全球健康
- 发育儿科 发育儿科
- 流行病学 流行病学
背景情况:
- 早产是发育性智力障碍 (PDID) 的重要危险因素.
- 了解早产儿PDID负担的全球趋势和差异对于有针对性的干预至关重要.
研究的目的:
- 从1990年到2021年,在全球范围内全面评估PDID在CABP中的患病率和残疾寿命 (YLDs).
- 在CABP中分析与PDID相关的趋势,年龄特异性负担和健康不平等.
主要方法:
- 使用的2021年全球疾病负担数据用于CABP (0-19年) 中的PDID.
- 雇员结合点回归,年龄期队列分析 (APC) 和跨国健康不平等分析.
- 检查了全球,区域和国家层面.
主要成果:
- 在2021年,全球有12,114,153个流行病例和915,937个YLD的PDID在CABP中,男性更高.
- 流行病例和YLDs呈现上升趋势;年龄标准化流行率略有下降.
- 在5岁以下的儿童中,PDID负担下降,但在社会人口统计指数 (SDI) 较低的地区,这一群体的风险最高.
结论:
- 在CABP中,PDID的整体全球负担在1990年至2021年之间有所上升.
- 在全球范围内,在5岁以下的儿童中观察到PDID负担显著下降.
- 尽管不平等程度下降,但SDI低的地区在CABP中仍然承担着PDID的重大负担.
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