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Updated: May 13, 2026

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婴儿体重的生长曲线模型:一个范围审查协议

Marta Alves1,2,3, Sofia Serra2,4, Teresa Costa2,4

  • 1Epidemiology and Statistics Unit, Research Center, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, Lisbon, Portugal.

JBI evidence synthesis
|February 12, 2025
PubMed
概括

本范围审查系统地分析婴儿体重增长曲线的统计模型. 它检查了各种研究设计,样本大小和统计方法,以了解它们在估计婴儿生长轨迹中的应用.

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Population Growth00:57

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Pharmacokinetic Models: Comparison and Selection Criterion

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
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Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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The correlation between a drug's dosage and its impact on a biological system is a cornerstone of pharmacology and toxicology. Conventional dose–response curves, which include graded and quantal relationships, are key to this understanding. Graded dose–response curves depict the spectrum of a biological reaction to different doses within an individual, indicating that as the drug dosage increases, so does the intensity of the response. On the other hand, quantal dose–response relationships...
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