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Updated: May 28, 2025

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

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炎症和瘤的免疫逃逸是对DNA损伤的反应

Naoe Taira Nihira1, Rei Kudo2, Tomohiko Ohta1

  • 1Department of Translational Oncology, St. Marianna University Graduate School of Medicine, Kawasaki, Japan.

Seminars in cancer biology
|February 12, 2025
PubMed
概括

衰老和癌细胞具有相同的炎症特征,影响瘤微环境和免疫反应. 通过cGAS-STING通路了解炎症是开发癌症疗法的关键,这些疗法可以将"冷"瘤转化为"热"瘤,以提高治疗效率.

关键词:
在CGAS-STING中,我们可以看到CGAS-STING.对DNA损伤的反应反应炎症 炎症是一种炎症.在 NF-kBB 中.在PD-L1中.

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