在怀孕早期和婴儿听力损失期间使用酒精,大麻和尼古丁
Kelly C Young-Wolff1, Nina Oberman2, Stacey E Alexeeff2
1Division of Research, Kaiser Permanente Northern California, Pleasanton, California, United States of America; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, United States of America; Department of Health Systems Science, Bernard J. Tyson Kaiser Permanente School of Medicine, Pasadena, CA, United States of America.
Preventive medicine
|February 12, 2025
概括
怀孕期间母亲饮酒与婴儿听力损失的风险更高有关. 这项研究发现,产前酒精暴露与婴儿在生命前六个月的听力损伤之间存在显著的关联.
科学领域:
- 产科和妇科 产科和妇科
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 产前物质暴露是婴儿健康的一个重大问题.
- 了解酒精,大麻和尼古丁对幼儿发育的影响至关重要.
研究的目的:
- 调查母亲在产前使用酒精,大麻或尼古丁与在孩子出生前六个月内诊断出听力损失之间的关联.
主要方法:
- 一项基于人口的回顾性出生队列研究包括2011年至2023年间出生的297,147名婴儿.
- 孕妇使用物质 (酒精,大麻,尼古丁) 在怀孕早期进行了查.
- 婴儿听力损失通过电子健康记录中的ICD代码来识别;修改Poisson回归分析了风险比率.
主要成果:
- 产前酒精使用与婴儿听力损失的风险增加有关 (调整后RR: 1.37;95%CI: 1.05-1.79).
- 在产前使用大麻或尼古丁与婴儿听力损失之间没有发现显著的关联.
- 在研究队列中的0.2%的婴儿在生命的前六个月内接受了听力损失诊断.
结论:
- 怀孕早期母亲饮酒与婴儿听力损失诊断的风险更高有关.
- 这些发现强调了解决产前酒精暴露的重要性,以减轻潜在的婴儿健康风险.
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