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Updated: May 28, 2025

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry
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Published on: January 6, 2017

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确定TNFAIP2作为CSF-1受体激活的独特细胞调节剂

Randa A Abdelnaser1, Masateru Hiyoshi2, Naofumi Takahashi1

  • 1Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.

Life science alliance
|February 12, 2025
PubMed
概括

细胞蛋白TNFAIP2通过PIP2结合促进其聚合,从而调节CSF-1受体 (CSF1R) 的激活. 这种机制增强了CSF1R二分化和巨细胞的反应,提供了治疗见解.

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