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Updated: May 28, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

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高通量查确定了光激酶B作为默克尔细胞癌的关键治疗标

Tara Gelb1, Khalid A Garman1, Daniel Urban2

  • 1Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

Nature communications
|February 12, 2025
PubMed
概括

研究人员选化合物,以找到新的默克尔细胞癌 (MCC) 治疗方法. 光激酶B (AURKB) 抑制剂,如AZD2811,显示出希望,特别是对病毒阳性MCC,减少小鼠的瘤生长.

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