重复的哨兵淋巴结活检检查乳房保护手术后局部复发
Yuka Matsubara1, Nobuyasu Suganuma2, Shogo Nakamoto3
1Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-Ku, Yokohama, 236-0004, Japan. Matsubara.yuk.jq@yokohama-cu.ac.jp.
Breast cancer (Tokyo, Japan)
|February 12, 2025
概括
重复的哨兵淋巴结活检 (reSNB) 在初始手术后对乳腺瘤复发 (IBTR) 有效. 它显示了高的鉴定率和没有局部复发,这表明它对治疗乳腺癌具有临床意义.
科学领域:
- 手术瘤学手术瘤学
- 乳腺癌管理 乳腺癌管理
- 核医学在瘤学中的应用
背景情况:
- 哨兵淋巴结活检 (SNB) 是早期乳腺癌的标准,可以忽略状淋巴结解剖 (Ax),同时保持状控制.
- 阴侧乳腺瘤复发 (IBTR) 需要进一步的管理策略.
- 评估重复SNB (reSNB) 对IBTR患者至关重要.
研究的目的:
- 评估重复哨兵淋巴结活检 (reSNB) 的有效性和安全性,用于乳腺瘤复发 (IBTR) 的患者.
- 为了确定 reSNB 在股中的识别率.
- 评估癌症结局,包括转移和局部复发,在 reSNB 之后.
主要方法:
- 在2012年6月至2019年3月期间,对52名接受IBTR reSNB治疗的患者进行了回顾性分析.
- reSNB使用染料和放射性同位素方法进行.
- 识别率计算为可视化的SLN,除以病例总数,比较初始手术程序.
主要成果:
- 总体而言,reSNB的识别率为94.2%.
- 在最初接受SNB治疗的患者中,对于reSNB的识别率更高,而不是轴心淋巴结剖析 (83.3%对42.9%).
- 三名患者 (6.7%) 呈阳性resSNB在ipsilateral下;在 contralateral下或内部乳腺区域没有转移. 在经过再手术后的ipsilateral股区域没有观察到局部复发.
结论:
- 在IBTR案件中,reSNB实现了高的识别率,与最初的SNB相美.
- reSNB 显示出较低的阳性转移率,并有效地防止 ipsilateral 带区域的局部复发.
- 结果表明,尽管样本规模有限,reSNB对于管理IBTR具有临床意义.
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