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Updated: May 28, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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角胺对人类肝细胞P450酶的抑制作用

Yanmo Yang1, Ke Zhang2, Mi Zhou3

  • 1Department of Pharmacy, Changde Hospital, Xiangya School of Medicine, Central South University (The First People's Hospital of Changde City), No. 388, Renmin Road, Wuling District, Changde City, 415000, Hunan Province, China.

Naunyn-Schmiedeberg's archives of pharmacology
|February 12, 2025
PubMed
概括

在Cornus officinalis中发现的Cornuside抑制了关键的P450 (CYP) 酶,包括CYP3A4,CYP2C19和CYP2E1. 这种相互作用表明,当Cornuside与这些酶代谢的药物同时使用时,可能存在药物相互作用.

关键词:
科尔努斯的一面细胞染色体P450的使用.人类肝脏显微体抑制抑制的抑制作用

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